неделя, 6 март 2011 г.

L-norvalin

L-norvalin (L-Norvaline) is a synthetic amino acid that is not found in animal proteins, including humans. L-norvalinat an analogue and a modified version of the branched amino acid L-valine. In the body it affects the metabolism of arginine and vasodilation. How it affects the muscles? Find out for yourself.
Stereoisomers of norvalina have different taste: L-norvalin - bitter, D-norvalin - sweet. In chemical properties norvalinat typical aliphatic amino acid. Not involved in the composition of proteins.
In the body of animals is the antagonist of valine and leucine. L-norvalinat (L-2-aminopentanoic-acid) is an isomer of L-valine. However, it has its physiological functions. Physiological functions of L-norvalin
Some time ago was considered that norvalinat has no physiological activity. However, studies found that L-norvalinat have a strong impact on the metabolism of arginina.Toy is able to block the activity of arginazata - enzyme, lowering the concentration of arginine in the human body.
The strong inhibitory effect on norvalina arginazata is the result of its structural analogy with ornithine, which is involved in the regulation of activity arginaznata the principle of feedback. Thus increases the concentration of free arginine in the blood, and he released pathways leading to its transformation into nitric oxide (NO).
The latter increases the concentration by up to 60%, causing vasodilation (widening of blood vessels), respectively, accelerates the transport of nutrients to the bloodstream and they reach the muscle and thus increasing muscle tone and growth.
It thus gets the full "inflated effect" on the cells and muscles.
With this feature norvalinat a worthy alternative to arginine, a combination of norvalin and arginine has a synergistic effect.
Bodybuilders and athletes are constantly looking for ways to "unlock" the natural ability of their body use nitric oxide more effectively.
Thanks to breakthroughs in the field of sports medicine is now known about the production of sodium oxide and its link with better physical performance and impressive athletes. Basic properties attributed to the L-norvalin:

    
* Nitric oxide (NO) promoter;
    
* Restores and strengthens blood vessels;
    
* Enhances blood flow;
    
* Leads to increased generation of energy in time due to better transport of substances;
    
* Increases endurance;
    
* Reduces inflammation.
What doses are recommended and how to accept L-norvalin?
Standard dose: 50-200 mg. Contraindications and side effects
In healthy people, there were no side effects, toxicity, drug and food interactions.
You need to be approached with caution when combining L-norvalin with L-arginine in high doses, as this leads to hiperargininemiya, because of the synergistic effect on increasing the NO-concentration.
People with low blood pressure should approach with caution in dosage. Admission by diabetics should be tailored to diet and insulin program. It is best to happen by the supervising physician.
Note: Do not take norvalin in liver disease. Prohibited use in subjects with or argininemiya arginazen deficiency (rare genetic disorder), because L-norvalinat is a potent inhibitor arginazen.
In pregnancy, diabetes, hypoglycemia and other medical conditions requiring medication, is necessary consultation with a physician or pharmacist before taking any nutritional supplements. Which sports and health supplements we can meet?
The most usual place to meet norvalin L-label is a nitrogen compound buusteri. The dosage varies and there shall comply with the doses and the presence of other precursors of nitric oxide, including arginine, ornithine, histindin and other substances affecting blood supply such as Yohimbine and others.

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